Temporal changes in the outbreak of amyotrophic lateral sclerosis/Parkinsonism-dementia complex, evaluation of Guamanian Chamorro controls
β Scribed by Yuan, Ya-Xian; Liu, Yan; Xu, Min-Min; Yao, Jian-Lin; Gu, Ren-Ao
- Book ID
- 124145299
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 171 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0197-4580
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## Abstract To clarify the genetic background of amyotrophic lateral sclerosis (ALS)/parkinsonismβdementia complex (PDC) of the Kii peninsula, Japan (Kii ALS/PDC), we performed extended mutation analyses of three patients with pathologically diagnosed Kii ALS/PDC. Direct sequencing analyses were pe
## Abstract Amyotrophic lateral sclerosisβparkinsonism dementia complex (ALS/PDC) is a distinct neurodegenerative disorder characterized by ALS pathology with neurofibrillary tangles (NFTs) in the spinal cord and brain. Recent clinical studies have revealed a high incidence and a high familial occu