Multiple studies demonstrate that manganese (Mn) exposure potentiates inflammatory mediator output from activated glia; this increased output is associated with enhanced mitogen activated protein kinase (MAPK: p38, ERK and JNK) activity. We hypothesized that Mn activates MAPK by activating the kinas
β¦ LIBER β¦
Temporal and quantitative regulation of mitogen-activated protein kinase (MAPK) modulates cell motility and invasion
β Scribed by Krueger, Joseph S; Keshamouni, Venkateshwar G; Atanaskova, Natasha; Reddy, Kaladhar B
- Book ID
- 110064808
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 327 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0950-9232
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## Abstract Enhanced oxidative stress is a common feature of liver diseases and contributes to chronic liver disease (CLD) progression by inducing fibrogenesis during liver regeneration. Peroxidation products of cholesterol metabolism, named oxysterols, are new and reliable markers of oxidative str