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TEMPOL protects human neuroblastoma SH-SY5Y cells against ß-amyloid-induced cell toxicity

✍ Scribed by Pennapa Chonpathompikunlert; Junkyu Han; Kazuko Toh; Hiroko Isoda; Yukio Nagasaki

Book ID
113589049
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
305 KB
Volume
650
Category
Article
ISSN
0014-2999

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## Abstract We investigated the effect of vanadate, a tyrosine phosphatase inhibitor, on cell death induced by peroxynitrite in human neuroblastoma SH‐SY5Y cells. Vanadate prevented cell death induced by 3‐morpholinosydnonimine (SIN‐1), a peroxynitrite donor; whereas SIN‐1‐induced cell death was no