Template-directed synthesis of acyclic oligonucleotide analogues
β Scribed by J. Visscher; Alan W. Schwartz
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 293 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-2844
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A simulation model is proposed for the template- and sequence-directed (TSD) condensation of two trideoxyribonucleotide 3'-phosphate molecules into a hexameric template with palindromic sequence studied experimentally by von Kiedrowski (1986;Angew. Int. Ed. Engl.25, 932--935). The model simulates re
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