Temperature-Responsive Polymers: Chemistry, Properties, and Applications

✍ Scribed by Georgiou, Theoni K.; Khutoryanskiy, Vitaliy V

• Publisher: John Wiley and Sons
• Year: 2018
• Tongue: English
• Leaves: 409
• Category: Library

✦ Synopsis

An authoritative resource that offers an understanding of the chemistry, properties and applications of temperature-responsive polymersWith contributions from a distinguished panel of experts, Temperature-Responsive Polymers puts the focus on hydrophilic polymers capable of changing their physicochemical properties in response to changes in environmental temperature. The contributors review the chemistry of these systems, and discuss a variety of synthetic approaches for preparation of temperature-responsive polymers, physicochemical methods of their characterisation and potential applications in biomedical areas. The text reviews a wide-variety of topics including: The characterisation of temperature-responsive polymers; Infrared and Raman spectroscopy; Applications of temperature-responsive polymers grafted onto solid core nanoparticles; and much more. The contributors also explore how temperature-responsive polymers can be used in the biomedical field for applications such as tissue engineering. This important resource:Offers an important synthesis of the current research on temperature-responsive polymersCovers the chemistry, the synthetic approaches for presentation and the physiochemical method of temperature-responsive polymersIncludes a review of the fundamental characteristics of temperature-responsive polymersExplores many of the potential applications in biomedical science, including drug delivery and gene therapyWritten for polymer scientists in both academia and industry as well as postgraduate students working in the area of stimuli-responsive materials, this vital text offers an exploration of the chemistry, properties and current applications of temperature-responsive polymers.  Read more...

Abstract: An authoritative resource that offers an understanding of the chemistry, properties and applications of temperature-responsive polymersWith contributions from a distinguished panel of experts, Temperature-Responsive Polymers puts the focus on hydrophilic polymers capable of changing their physicochemical properties in response to changes in environmental temperature. The contributors review the chemistry of these systems, and discuss a variety of synthetic approaches for preparation of temperature-responsive polymers, physicochemical methods of their characterisation and potential applications in biomedical areas. The text reviews a wide-variety of topics including: The characterisation of temperature-responsive polymers; Infrared and Raman spectroscopy; Applications of temperature-responsive polymers grafted onto solid core nanoparticles; and much more. The contributors also explore how temperature-responsive polymers can be used in the biomedical field for applications such as tissue engineering. This important resource:Offers an important synthesis of the current research on temperature-responsive polymersCovers the chemistry, the synthetic approaches for presentation and the physiochemical method of temperature-responsive polymersIncludes a review of the fundamental characteristics of temperature-responsive polymersExplores many of the potential applications in biomedical science, including drug delivery and gene therapyWritten for polymer scientists in both academia and industry as well as postgraduate students working in the area of stimuli-responsive materials, this vital text offers an exploration of the chemistry, properties and current applications of temperature-responsive polymers

✦ Table of Contents

Content: Cover
Title Page
Copyright
Contents
About the Editors
List of Contributors
Preface
Part I Chemistry
Chapter 1 Poly(N-isopropylacrylamide): Physicochemical Properties and Biomedical Applications
1.1 Introduction
1.2 PNIPAM as Thermosensitive Polymer
1.3 Physical Properties of PNIPAM
1.3.1 Phase Behavior of PNIPAM in Water/Alcohol Mixtures
1.3.2 Effect of Concentration and Molecular Weight of PNIPAM on LCST
1.3.3 Effect of Surfactants on LCST
1.3.4 Effect of Salts on LCST
1.4 Common Methods for Polymerization of NIPAM
1.4.1 Free Radical Polymerization. 1.4.2 Living Radical Polymerization1.4.2.1 ATRP of NIPAM
1.4.2.2 RAFT Polymerization of NIPAM
1.5 Dual Sensitive Systems
1.5.1 pH and Thermosensitive Systems
1.5.2 Reduction-Sensitive and Thermosensitive Systems
1.5.3 Hybrid-Thermosensitive Materials
1.6 Bioconjugation of PNIPAM
1.6.1 Protein-PNIPAM Conjugates
1.6.2 Peptide-PNIPAM Conjugates
1.6.3 Nucleic Acid-PNIPAM Conjugates
1.7 Liposome Surface Modification with PNIPAM
1.8 Applications of PNIPAM in Cell Culture
1.9 Crosslinking Methods for Polymers
1.9.1 Crosslinking in PNIPAM-Based Hydrogels. 1.9.2 Crosslinking of PNIPAM-Based Micelles1.9.2.1 Shell Crosslinked (SCL)
1.9.2.2 Core Crosslinked (CCL)
1.10 Conclusion and Outlook of Applications of PNIPAM
Acknowledgments
References
Chapter 2 Thermoresponsive Multiblock Copolymers: Chemistry, Properties and Applications
2.1 Introduction
2.2 Chemistry of Thermoresponsive Block-based Copolymers
2.3 Architecture, Number of Blocks and Block Sequence
2.3.1 Why the Block Structure?
2.3.2 Triblock Copolymers
2.3.2.1 Micelles
2.3.2.2 Gels
2.3.2.3 Films and Membranes
2.3.3 Tetrablock Copolymers
2.3.4 Pentablock Copolymers. 2.3.4.1 Pluronic® Based2.3.4.2 Non-pluronic Based
2.3.5 Multiblock Copolymers
2.4 Applications
2.5 Conclusions
Acknowledgments
References
Chapter 3 Star-shaped Poly(2-alkyl-2-oxazolines): Synthesis and Properties
3.1 Introduction
3.2 Synthesis of Star-shaped Poly(2-alkyl-2-oxazolines)
3.3 Properties of Star-shaped Poly(2-alkyl-2-oxazolines)
3.4 Conclusions
References
Chapter 4 Poly(N-vinylcaprolactam): From Polymer Synthesis to Smart Self-assemblies
4.1 Introduction
4.2 Synthesis of PVCL Homo- and Copolymers
4.2.1 Synthesis of Statistical PVCL Copolymers. 4.2.2 Synthesis of PVCL Block Copolymers4.2.3 Other PVCL-based Copolymers
4.3 Properties of PVCL in Aqueous Solutions
4.3.1 Dependence of the LCST of PVCL on Molecular Weight and Polymer Concentration
4.3.2 LCST Dependence on Chemical Composition
4.3.3 The Effect of Salt on the PVCL Temperature Response
4.3.4 The Effect of Solvent on PVCL Temperature Response
4.4 Assembly of PVCL-based Polymers in Solution
4.4.1 PVCL Interpolymer Complexes
4.4.2 PVCL-based Micelles
4.4.3 Self-assembly of PVCL-based Copolymers into Polymersomes
4.5 Templated Assemblies of PVCL Polymers.

✦ Subjects

Thermoresponsive polymers.;TECHNOLOGY & ENGINEERING -- Chemical & Biochemical.