Temperature effects on photosensitized processes

✍ Scribed by V. Gottfried; S. Kimel

• Book ID: 103993229
• Publisher: Elsevier Science
• Year: 1991
• Tongue: English
• Weight: 787 KB
• Volume: 8
• Category: Article
• ISSN: 1011-1344
• DOI: 10.1016/1011-1344(91)80116-y

✦ Synopsis

The singlet-oxygen-mediated reaction of meso-tetraphenylporphine tetrasulphonate (TPPS4) with different chemical acceptors in buffered aqueous solution was studied as a function of temperature. Imidazole, tryptophan, dimethyl p-nitrosoaniline, (RNO) and furfuryl alcohol served as acceptors. The measurements were performed in real time by spectroscopic or electrochemical monitoring of the consumption of the various reagents, acceptors or dissolved oxygen as a function of the absorbed energy. The results show the following increases in the reaction rate over the temperature range 15-45 degrees C: tryptophan (86%), RNO (90%), furfuryl alcohol (150%) and imidazole (210%). The influence of temperature-correlated changes in the initial oxygen concentration and pH was investigated. Possible implications of the present results for the synergistic influence of hyperthermia and photodynamic therapy are discussed.