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Temperature-dependent activation of recombinant rat vanilloid VR1 receptors expressed in HEK293 cells by capsaicin and anandamide

โœ Scribed by J Sprague; C Harrison; D.J Rowbotham; D Smart; D.G Lambert


Book ID
114014056
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
72 KB
Volume
423
Category
Article
ISSN
0014-2999

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## Abstract Bradykinin (BK) and angiotensin II (AngII) often have opposite roles in cardiovascular diseases. Our aim here was to construct hybrid receptors which bind AngII but signal as BK. Various sequences of the intracellular face of the AngII type I receptor, AT1R, were replaced with correspon