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Temperature-dependence of lethal and mutagenic actions of HNO2 on phage T4

โœ Scribed by Ishiwa, Hiromi; Yan, Yonhon; Kondo, Sohei

Book ID
123251453
Publisher
Elsevier Science
Year
1964
Weight
169 KB
Volume
91
Category
Article
ISSN
0926-6550

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A temperature sensitive ligase allele of phage T4 reduced or eliminated HNO2 induced reversion of am mutants. Since at the temperatures used, the ligase mutant is defective in the repair of some types of lethal lesions (i.e., UV, MMS and EMS induced lesions) these results indicate that HNO2 mutagene