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Temperature dependence of L-type calcium channel currents in isolated smooth muscle cells from the rat tail artery

โœ Scribed by Rui Wang; Edward Karpinski; Peter K.T. Pang


Book ID
107957268
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
439 KB
Volume
16
Category
Article
ISSN
0306-4565

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The patch-clamp method has been used to investigate the action of caffeine on the calcium current (Ic,) in single isolated smooth muscle cells of the guineapig ileum. Caffeine (10 mM) substantially inhibited Ic,. This effect occurred in a biphasic manner and it was not due either to activation of ad