A series of 14 3-substituted 4-oxoquinolones with or without a substituent (methyl, ethyl) in position 1 were prepared. Literature and measured data were used to study the inÑuence of the substituent on the shifts of carbon atoms of these compounds, which are model compounds for antibacterial drugs
Temperature and solvent variation of the 13C and 1H NMR spectra of r-1,t-2,c-3,t-4-tetrachlorotetralin
✍ Scribed by Graham A. Bowmaker; David J. Calvert; Peter B. D. de la Mare; Alan J. Jones
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 310 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0749-1581
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✦ Synopsis
Abstract
Vicinal coupling constants in the ^1^H and ^13^C NMR spectra of r‐1,t‐2,c‐3,t‐4‐tetrachlorotetralin change with temperature and solvent in a manner better explained by conformational equilibration than by intramolecular or solvent‐determined distortions.
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