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Temperature and solvent effects in the solubility of some pharmaceutical compounds: Measurements and modeling

✍ Scribed by Fátima L. Mota; Aristides P. Carneiro; António J. Queimada; Simão P. Pinho; Eugénia A. Macedo

Book ID
113592189
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
316 KB
Volume
37
Category
Article
ISSN
0928-0987

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✍ Feelly Ruether; Gabriele Sadowski 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 182 KB 👁 1 views

The knowledge of the solubility of pharmaceuticals in pure solvents and solvent mixtures is crucial for designing the crystallization process of drug substances. The first step in finding optimal crystallization conditions is usually a solvent screening. Since experiments are very time consuming, a