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Temozolomide does not increase overall survival in recurrent malignant glioma

✍ Scribed by Roger Stupp


Book ID
114483874
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
81 KB
Volume
3
Category
Article
ISSN
1363-4054

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## Abstract Radiotherapy plus concomitant and adjuvant temozolomide have demonstrated improved survival for glioblastoma. However, prognosis remains poor. High‐doses chemotherapy with carmustine is another way to improve response and survival by increasing the dose delivered. Myelotoxicity imposes