Telomeres and telomerase: more than the end of the line
โ Scribed by Mary-Lou Pardue; P. G. DeBaryshe
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 161 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0009-5915
No coin nor oath required. For personal study only.
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Telomerase RNA component (TERC) and telomerase reverse transcriptase (TERT) function together to elongate telomeres and to protect chromosomal ends. Recent studies have discovered that overexpression of telomerase's TERT subunit promoted epidermal stem-cell mobilization, hair growth and stem-cell pr
Chromosomes may be either circular or linear, the latter being prone to erosion caused by incomplete replication, degradation and inappropriate repair. Despite these problems, the linear form of DNA is frequently found in viruses, bacteria, eukaryotic nuclei and organelles. The high incidence of lin