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Telomere Shortening Is Associated with Cell Division in Vitro and in Vivo

✍ Scribed by Richard C. Allsopp; Edwin Chang; Mohammad Kashefi-Aazam; Evgeny I. Rogaev; Mieczyslaw A. Piatyszek; Jerry W. Shay; Calvin B. Harley

Book ID
115602154
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
563 KB
Volume
220
Category
Article
ISSN
0014-4827

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We studied telomere length in the peripheral blood leukocyte samples of a large group of patients with chronic myelogenous leukemia (CML) by Southern blot hybridization using the (TTAGGG)4 probe. The average telomere length expressed as the peak telomere repeat array (TRA) of the peripheral blood sa