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Telomerase upregulation in Barrett’s esophagus precedes the development of esophageal adenocarcinoma

✍ Scribed by Tarun Mullick; Jason E Tasch; Adrian H Ormsby; Joel E Richter; John Goldblum; Robert E Petras; Terry Gramlich; Thomas W Rice; John Cowell; Gary W Falk

Book ID
119390923
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
27 KB
Volume
96
Category
Article
ISSN
0002-9270

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## BACKGROUND. The rate of incidence of esophageal adenocarcinoma has surpassed that of all other malignancies in the U.S. Esophageal adenocarcinoma arises from Barrett's esophagus through the multistep accumulation of genetic mutations in metaplastic cells, accompanied by histologic changes from