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Telomerase activity level, but not hTERT mRNA and hTR level, regulates telomere length in telomerase-reconstituted primary fibroblasts

✍ Scribed by Susan J.J Swiggers; H.Arno J Nibbeling; Annelieke Zeilemaker; Marianne A Kuijpers; Karin A Mattern; J.Mark J.M Zijlmans

Book ID
116980996
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
444 KB
Volume
297
Category
Article
ISSN
0014-4827

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Telomerase activity and hTERT mRNA expre
Telomerase activity and hTERT mRNA expression can be heterogeneous and does not correlate with telomere length in soft tissue sarcomas
✍ Pu Yan; Jean Benhattar; Jean-Michel Coindre; Louis Guillou 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 278 KB

## Abstract In a previous study, we showed that telomerase activity (TA) and human telomerase reverse transcriptase (hTERT) mRNA expression were undetectable in benign mesenchymal lesions and low‐grade soft tissue sarcomas (STSs), but detectable in about 50% of intermediate‐/high‐grade STSs. We won