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Telomerase activity in well-differentiated papillary thyroid carcinoma corrrelates with advanced clinical stage of the disease

✍ Scribed by Leticia Bornstein-Quevedo; M. L. García-Hernández; Ignacio Camacho-Arroyo; Miguel F. Herrera; Arturo Angeles Angeles; Ofelia González Treviño; Armando Gamboa-Domínguez

Book ID: 107571734
Publisher: Springer US
Year: 2003
Tongue: English
Weight: 109 KB
Volume: 14
Category: Article
ISSN: 1046-3976
DOI: 10.1007/s12022-003-0013-3

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Cathepsin B (CB) and cathepsin L (CL) are cysteine endopeptidases involved in the processing of thyroglobulin (Tg) in the normal thyroid. As thyroglobulin expression is frequently altered in thyroid carcinomas, we have analyzed 42 human thyroid tissues from 40 patients to study the effect of maligna