Background and Objectives: Fas (APO-1) induces apoptosis after binding Fas ligand (FasL). Evidence suggests that tumors may use this interaction to evade the host immune response. Fas/FasL expression has not been reported in esophageal cancer. We hypothesized that Fas expression would render esophag
β¦ LIBER β¦
Telomerase activity in esophageal squamous cell carcinoma: Down-regulation by chemotherapeutic agent
β Scribed by Akira Mitsui; Yoshiyuki Kuwabara; Hirotaka Iwase; Masami Mitani; Noriyuki Shinoda; Atsushi Sato; Tatsuya Toyama; Masahiko Sugiura; Tomotaka Suzuki; Joji Kato; Yoshitaka Fujii
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 171 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0022-4790
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## Abstract ## BACKGROUND Previous reports indicate that Genistein, a naturally occurring isoflavonoid, exhibits strong antiangiogenic activity. The underlying mechanism of inhibition, however, remains unclear. Among the biologic effects of Genistein are the inhibition of tyrosine kinases and the