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Telomerase activity in central nervous system malignant lymphoma

โœ Scribed by Kunyu Harada; Kaoru Kurisu; Kazunori Arita; Takashi Sadatomo; Hidetoshi Tahara; Eiji Tahara; Toshinori Ide; Eiichi Tahara; Tohru Uozumi

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
109 KB
Volume
86
Category
Article
ISSN
0008-543X

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โœฆ Synopsis

BACKGROUND. Primary central nervous system malignant lymphoma (PCNSL) has been regarded as a rare neoplasm. Recently, however, its incidence has been rapidly increasing. Despite active clinical trials, its clinical and biologic features remain unknown and there has been no effective treatment or prognostic factor.

The current study attempted to elucidate telomerase activity and expression of the telomere-related RNA of PCNSL as novel prognostic factors.

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