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Telomerase activity coevolves with body mass not lifespan

✍ Scribed by Andrei Seluanov; Zhuoxun Chen; Christopher Hine; Tais H. C. Sasahara; Antonio A. C. M. Ribeiro; Kenneth C. Catania; Daven C. Presgraves; Vera Gorbunova

Book ID
111199358
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
381 KB
Volume
6
Category
Article
ISSN
1474-9718

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## Abstract In a majority of malignant human tumors telomerase activity can be detected, suggesting an immortal phenotype. Expression of the reverse transcriptase subunit, hTERT, in the human telomerase complex is required for telomerase activity. The regulation of hTERT, from gene level to a fully