Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease
โ Scribed by H Kojima; O Yokosuka; F Imazeki; H Saisho; M Omata
- Book ID
- 119755635
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 476 KB
- Volume
- 112
- Category
- Article
- ISSN
- 0016-5085
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๐ SIMILAR VOLUMES
Background and Objectives: Activation of telomerase and stabilization of telomeres are considered necessary for immortalization of tumor cells. Telomerase activity was analyzed in 69 hepatocellular carcinomas and adjacent chronic liver disease tissues. The telomerase activity level was examined in r
To assess the role of telomerase in the development of liposarcomas, we measured telomerase activity in 36 malignant and seven benign lipomatous neoplasias from 34 patients. A sensitive polymerase chain reactionbased telomerase assay (the telomeric repeat amplification protocol) was applied. Shorten