✦ LIBER ✦

Telomerase activity and expression of its RNA component in cervical lesions

✍ Scribed by Kazuo Yashima; Raheela Ashfaq; Jan Nowak; Vivian Von Gruenigen; Sara Milchgrub; Asha Rathi; Jorge Albores-Saavedra; Jerry W. Shay; Adi F. Gazdar

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 323 KB
Volume: 82
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19980401)82:7<1319::aid-cncr15>3.0.co;2-9

No coin nor oath required. For personal study only.

✦ Synopsis

of its RNA component (hTR) during the multistage pathogenesis of cervical carcinomas, and correlated activation with histopathologic findings and human papillo-

📜 SIMILAR VOLUMES

Differential telomerase activity, expres

Differential telomerase activity, expression of the telomerase catalytic sub-unit and telomerase-RNA in ovarian tumors

✍ Tjoung-Won Park; Sabine Riethdorf; Lutz Riethdorf; Thomas Löning; Fritz Jänicke 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 163 KB 👁 2 views

Telomerase activity has been found in a variety of malignant tumors but only rarely in benign tumors or normal tissues. In this study, we investigated telomerase activation in 37 ovarian tumors, including benign, borderline and malignant neoplasms. Telomerase activity was detected using the telomeri

Telomerase activity in cervical cancer i

Telomerase activity in cervical cancer is quantitatively distinct from that in its precursor lesions

✍ Satoru Kyo; Masahiro Takakura; Masaaki Tanaka; Taro Kanaya; Masaki Inoue 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 97 KB 👁 1 views

Studies using the telomeric repeat amplification protocol (TRAP) assay have demonstrated telomerase activity not only in cancers but also in non-cancerous lesions. However, quantitative differences in activity between both lesions have not been examined. In the present study, using a stretch PCR ass

Telomerase activity and its inhibition i

Telomerase activity and its inhibition in benign and malignant breast lesions

✍ Sugino, Takashi; Yoshida, Kazuhiro; Bolodeoku, John; Tarin, David; Goodison, Ste 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 121 KB 👁 1 views

Many types of human tumours and immortal cell lines have been demonstrated to exhibit telomerase activity with the recently formulated telomeric repeat amplification protocol (TRAP assay). However, a small proportion of undoubted tumour samples give a negative result and it has been postulated that,

Telomerase activity by TRAP assay and te

Telomerase activity by TRAP assay and telomerase RNA (hTR) expression are predictive of outcome in neuroblastoma

✍ Choi, L. Mi Rim ;Kim, Nam W. ;Zuo, Juan Juan ;Gerbing, Robert ;Stram, Dan ;Luken 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 105 KB

Telomerase activity in colorectal cancer

Telomerase activity in colorectal cancer and its relationship to bcl-2 expression

✍ Iida, Atsushi; Yamaguchi, Akio; Hirose, Kazuo 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 231 KB 👁 1 views

## Background and objectives: Telomerase is thought to be responsible for cell immortality, and bcl-2 has been demonstrated to regulate apoptosis. recent studies have shown a wide occurrence of telomerase activation and bcl-2 deregulation in human carcinoma cells. ## Methods: We examined telomera

Expression of telomerase genes correlate

Expression of telomerase genes correlates with telomerase activity in human colorectal carcinogenesis

✍ Pu Yan; Emilia P. Saraga; Hanifa Bouzourene; Fred T. Bosman; Jean Benhattar 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB 👁 1 views

The human telomerase enzyme is composed of two essential components, hTR, which acts as a template for reverse transcription, and hTERT, which is the putative catalytic subunit for the enzyme. Recent studies have demonstrated a good correlation between hTERT expression and telomerase activation, whe