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Tehranolide molecule modulates the immune response, reduce regulatory T cell and inhibits tumor growth in vivo

✍ Scribed by Shokoofe Noori; Mohammad Taghikhani; Zuhair M. Hassan; Abdolamir Allameha; Ali Mostafaei


Book ID
116757636
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
420 KB
Volume
47
Category
Article
ISSN
0161-5890

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## Abstract The suppressive activity of regulatory T cells (Treg) has been implicated as an important factor limiting immune mediated destruction of tumor cells. However, not much is known about the presence and function of Treg within tumors. Here we show in a syngeneic murine glioma model a time‐