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Techniques for high-resolution MR imaging of atherosclerotic plaque

✍ Scribed by Chun Yuan; Jay S. Tsuruda; Kirk N. Beach; Cecil E. Hayes; Marina S. Ferguson; Charles E. Alpers; Thomas K. Foo; D. Eugene Strandness

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
917 KB
Volume
4
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

Atherosclerotic cardiovascular disease is the most common cause of death in the United States. Investigation of atherosclerotic plaque morphology and composition is important because the findings may be useful in predicting prognosis or response to therapy. This study presents high‐resolution magnetic resonance (MR) imaging techniques developed on a 1.5‐T whole‐body imager with a custom‐built surface coil, for characterizing the composition and morphology of plaque removed at carotid endarterectomy. The initial comparison of MR imaging and histologic results showed good correlation. In conjunction with MR angiography, these techniques could be used in in vivo imaging to define the size, location, and contents of atherosclerotic plaque at the carotid bifurcation.

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