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Techniques and Pitfalls in the Detection of Pathogenic Mitochondrial DNA Mutations

✍ Scribed by Moraes, Carlos T.; Atencio, David P.; Oca-Cossio, Jose; Diaz, Francisca


Book ID
123042951
Publisher
American Society for Investigative Pathology
Year
2003
Tongue
English
Weight
786 KB
Volume
5
Category
Article
ISSN
1525-1578

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## Abstract More than 200 disease‐related mitochondrial DNA (mtDNA) point mutations have been reported in the Mitomap (http://www.mitomap.org) database. These mutations can be divided into two groups: mutations affecting mitochondrial protein synthesis, including mutations in tRNA and rRNA genes; a