Liver procurement and preparation for orthotopic liver transplantation (OLT) in the rat is the first stage for beginners aiming to acquire mastery of this model. It requires extensive and precise dissection in which each detail must provide security for the procurement and perfection for the future
Technical details for safer venous and biliary anastomoses for liver transplantation in the rat
✍ Scribed by Luc Delrivière; Paul Gibbs; Eiji Kobayashi; Shigeru Goto; Naoshi Kamada; Pierre Gianello
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 184 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0738-1085
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✦ Synopsis
Although orthotopic liver transplantation in the rat is a well-established experimental model, no detailed illustrated description of the procedure is available in the literature. As a result, achieving success in the technique without prolonged learning time requires training in specialized centers where the step-by-step details essential to success in the technique can be learnt. The aim of this paper is to provide beginners with the culminative experience of 15 years of improvements made to Kamada's original model, clearly illustrating the necessary steps and fine detail of each anastomosis to help beginners avoid unnecessary complications. We hope that this complete description of orthotopic liver transplantation in the rat, which remains the most difficult rodent transplant model to master, will greatly help microsurgeons acquire this demanding procedure.
📜 SIMILAR VOLUMES
To study the immunological and metabolic effects of auxiliary liver transplantation (ALT), a simple ALT model in rats was developed using the cuff application. Effects of transient parking of normal liver were tested in congenitally hyperbilirubinemic Gunn rats. Serum bilirubin concentrations in Gun