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Tec family kinases: Itk signaling and the development of NKT αβ and γδ T cells

✍ Scribed by Qian Qi; Arun Kumar Kannan; Avery August

Book ID
111313883
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
315 KB
Volume
278
Category
Article
ISSN
1432-1327

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## Abstract Cytoplasmic protein‐tyrosine kinases (PTKs) are enzymes involved in transducing a vast number of signals in metazoans. The importance of the Tec family of kinases was immediately recognized when, in 1993, mutations in the gene encoding Bruton's tyrosine kinase (Btk) were reported to cau