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Tec Family Kinases in Inflammation and Disease

✍ Scribed by Horwood, Nicole J.; Urbaniak, Ania M.; Danks, Lynett

Book ID
121302646
Publisher
Informa plc
Year
2012
Tongue
English
Weight
711 KB
Volume
31
Category
Article
ISSN
0883-0185

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## Abstract Cytoplasmic protein‐tyrosine kinases (PTKs) are enzymes involved in transducing a vast number of signals in metazoans. The importance of the Tec family of kinases was immediately recognized when, in 1993, mutations in the gene encoding Bruton's tyrosine kinase (Btk) were reported to cau