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Tea contains potent inhibitors of tyrosine phosphatase PTP1B

โœ Scribed by Junfeng Ma; Zhe Li; Shu Xing; Wan-Ting Tina Ho; Xueqi Fu; Zhizhuang Joe Zhao


Book ID
116301504
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
369 KB
Volume
407
Category
Article
ISSN
0006-291X

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Discovery and SAR of novel, potent and s
โœ Zhonghua Pei; Xiaofeng Li; Gang Liu; Cele Abad-Zapatero; Tom Lubben; Tianyuan Zh ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 211 KB

A salicylate second site binder was linked to three classes of phosphotyrosine mimetics to produce potent protein tyrosine phosphatase 1B (PTP1B) inhibitors which exhibit significant selectivity against other phosphatases including the most homologous member, TCPTP.