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TDP-43 pathology in familial British dementia

✍ Scribed by Claudia Schwab; Tetsuaki Arai; Masato Hasegawa; Haruhiko Akiyama; Sheng Yu; Patrick L. McGeer


Book ID
106073789
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
583 KB
Volume
118
Category
Article
ISSN
0001-6322

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## Abstract To identify novel causes of familial neurodegenerative diseases, we extended our previous studies of TAR DNA‐binding protein 43 (TDP‐43) proteinopathies to investigate __TDP‐43__ as a candidate gene in familial cases of motor neuron disease. Sequencing of the __TDP‐43__ gene led to the