✦ LIBER ✦

TCR usage in CTLs recognizing melanoma/melanocyte antigens

✍ Scribed by Markus J. Maeurer; Dina M. Martin; Walter J. Storkus; Michael T. Lotze

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 457 KB
Volume: 16
Category: Article
ISSN: 0167-5699
DOI: 10.1016/0167-5699(95)80084-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Presence on a human melanoma of multiple

Presence on a human melanoma of multiple antigens recognized by autologous CTL

✍ B. Den Van Eynde; P. Hainaut; M. Hérin; A. Knuth; C. Lemoine; P. Weynants; P. De 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 French ⚖ 716 KB

We derived from blood lymphocytes of a melanoma patient a large number of cytolytic T-cell clones directed against a cell line of the autologous tumor. Three distinct groups of antigens were recognized by these CTL on the autologous melanoma cells: group A consisted of stable antigens present on all

Analysis of antigens recognized on human

Analysis of antigens recognized on human melanoma cells by A2-restricted cytolytic t lymphocytes (CTL)

✍ T. Wölfel; M. Hauer; E. Klehmann; V. Brichard; B. Ackermann; A. Knuth; T. Boon; 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 780 KB

## We have pursued our analysis of potential tumor-rejection antigens recognized on human melanoma by autologous cytolytic T lymphocytes (CTL). We reported previously that 3 distinct antigens ( A,B,C) were recognized on melanoma cell line SK29-MEL in association with HLA-A2. Selection for melanoma

Melanoma antigen-encoding gene expressio

Melanoma antigen-encoding gene expression in melanocytic naevi and cutaneous malignant melanomas

✍ BASARAB; PICARD; SIMPSON; RUSSELL-JONES 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB

Melanoma antigen-encoding (MAGE) genes encode peptides which are expressed by a proportion of malignant melanomas (MMs) and can be recognized in vitro by autologous cytolytic T lymphocytes in a human leucocyte-associated antigen (HLA)-restricted manner. Although expression of MAGE genes has been stu

Identification of a novel peptide derive

Identification of a novel peptide derived from the melanocyte-specific gp100 antigen as the dominant epitope recognized by an HLA-A2.1-restricted anti-melanoma CTL line

✍ Alexander B. H. Barker; Marco W. J. Schreurs; Gaalda Tafazzul; Annemiek J. De Bo 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 633 KB

## Abstract Cytotoxic T lymphocytes (CTL) reactive with human melanoma tumor cells occasionally display cross‐reactivity with normal melanocytes. Previously, we identified the melanocyte lineage‐specific antigen gp100 that is expressed by both melanoma cells and normal melanocytes, as a target anti

Qualitative difference between the cytot

Qualitative difference between the cytotoxic T lymphocyte responses to melanocyte antigens in melanoma and vitiligo

✍ Belinda Palermo; Silvia Garbelli; Stefania Mantovani; Elisabetta Scoccia; Gian A 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 253 KB 👁 2 views

Vitiligo is a skin disorder characterized by depigmented macules secondary to melanocyte loss. An unusual facet is its relation to melanoma: Cytotoxic T lymphocytes directed to melanocyte antigens are found in both conditions and imply a breakdown of tolerance, yet the resulting immune reaction is t

Immunoselection in vivo: Independent los

Immunoselection in vivo: Independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma

✍ Elke Jäger; Mark Ringhoffer; Michael Altmannsberger; Michael Arand; Julia Karbac 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 211 KB 👁 2 views

Peptides derived from melanocyte differentiation antigens have been identified as targets for MHC class I-restricted cytolytic T lymphocytes (CTLs) in human melanoma Regression of antigen-expressing tumors as well as selection of antigen-loss variants in the presence of antigen-specific CTLs have pr