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TCR-independent T cell development mediated by gain-of-oncogene function or loss-of-tumor-suppressor gene function

✍ Scribed by Heinz Jacobs


Book ID
115648050
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
366 KB
Volume
12
Category
Article
ISSN
1044-5323

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## Abstract Immortal, nontumorigenic cell lines of Syrian hamster embryo (SHE) cells with different tumor‐suppressing activity were isolated. Subclones from the parental cells were isolated that either had retained (supB^+^) or lost (supB^βˆ’^) the ability to suppress tumorigenicity after hybridizati