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TCF Is the Nuclear Effector of the β-Catenin Signal That Patterns the Sea Urchin Animal–Vegetal Axis

✍ Scribed by Alin Vonica; Wei Weng; Barry M. Gumbiner; Judith M. Venuti


Book ID
115598295
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
528 KB
Volume
217
Category
Article
ISSN
0012-1606

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## Abstract The entry of β‐catenin into vegetal cell nuclei beginning at the 16‐cell stage is one of the earliest known molecular asymmetries seen along the animal–vegetal axis in the sea urchin embryo. Nuclear β‐catenin activates a vegetal signaling cascade that mediates micromere specification an