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TCDD Reduces Rat Hepatic Epidermal Growth Factor Receptor: Comparison of Binding, Immunodetection, and Autophosphorylation

โœ Scribed by C.H. Sewall; G.C. Clark; G.W. Lucier


Book ID
112265882
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
996 KB
Volume
132
Category
Article
ISSN
0041-008X

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Kinetic analysis of the tissue distribution of human epidermal growth factor (hEGF) in rats was performed in vivo. The plasma disappearance half-life of [125I]hEGF was prolonged by coadministration of unlabeled hEGF, indicating saturation of the mechanism for hEGF removal from the systemic circulati