Mutational analysis of the PTEN gene in
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Xiyun Shao; Raj Tandon; Ghassan Samara; Hiroaki Kanki; Hiroko Yano; Lanny G. Clo
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Article
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1998
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John Wiley and Sons
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French
β 121 KB
π 2 views
## Loss of heterozygosity (LOH ) at chromosome band 10q23 occurs frequently in a wide variety of human tumors. A recently identified candidate tumor suppressor gene, PTEN located on 10q23, is mutated in multiple advanced cancers. To explore whether PTEN is associated with human squamous cell carci