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Taxol-induced ceramide generation and apoptosis in human breast cancer cells

โœ Scribed by Anthony G. Charles; Tie-Yan Han; Yong Y. Liu; Nora Hansen; Armando E. Giuliano; Myles C. Cabot

Publisher
Springer
Year
2001
Tongue
English
Weight
136 KB
Volume
47
Category
Article
ISSN
0344-5704

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## Abstract Taxol is extensively used clinically for chemotherapy of patients with ovarian, breast, and lung cancer. Although taxol induces apoptosis of cancer cells, its exact mechanism of action is not yet known. To determine the mechanism of action of taxol in ovarian cancer, we tested the effec