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Taxol® and baccatin III production in suspension cultures of Taxus baccata and Taxus wallichiana in an airlift bioreactor

✍ Scribed by Alberto Navia-Osorio; Hermann Garden; Rosa M. Cusidó; Javier Palazón; A. Wilhelm Alfermann; M. Teresa Piñol


Book ID
117851175
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
82 KB
Volume
159
Category
Article
ISSN
0176-1617

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To achieve a better understanding of taxol metabolism and accumulation in Taxus cell cultures, a T. baccata cell line growing for 20 days in a selected growth medium was treated at the beginning of the experiment with several concentrations of taxol (25, 50, 100 and 200mgL(-1)). Compared with an unt