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Taxanes as adjuvant for breast cancer

✍ Scribed by Aron Goldhirsch; Prudence Francis; Monica Castiglione-Gertsch; Richard D Gelber; Alan S Coates

Book ID
117293685
Publisher
The Lancet
Year
2000
Tongue
English
Weight
96 KB
Volume
356
Category
Article
ISSN
0140-6736

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## Abstract Few predictive markers exist for response to adjuvant chemotherapy in breast cancer. The 78‐kDa glucose‐regulated protein (GRP78) is a potent antiapoptotic factor, conferring drug resistance. Recently, we reported that high GRP78 expression in breast cancer specimens predicts a shorter