Tautomérie Dans la Série des Pyrazolinones: I. Influence du Solvant Sur L'Équilibre Prototropique de la 1,3-Diméthylpyrazoline-5-one

✍ Scribed by A. Maquestiau; Y. van Haverbeke; R. Jacquerye

• Publisher: Wiley (John Wiley & Sons)
• Year: 2010
• Weight: 407 KB
• Volume: 80
• Category: Article
• ISSN: 0037-9646
• DOI: 10.1002/bscb.19710800103

✦ Synopsis

The tautomerisrn between CH, N H and OH forms of 1,3-dimethylpyrazoline-5-one has been investigated by use of I.R., N.M.R. and U.V. spectroscopy. In non polar solvents only the CH form is observed. In aprotic solvents, a linear relationship is obtained between the percent of the CH form and the basicity of the solvents, the decrease of CH form being in favor of the OH structure.

In protic solvents it is difficult to discern the effect of acidity and dielectric constant in the appearance of the NH form.