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Tautomycin suppresses growth and neuroendocrine hormone markers in carcinoid cells through activation of the Raf-1 pathway

✍ Scribed by Scott N. Pinchot; Joel T. Adler; Yinggang Luo; Jianhua Ju; Wenli Li; Ben Shen; Muthusamy Kunnimalaiyaan; Herbert Chen

Book ID: 116216460
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 657 KB
Volume: 197
Category: Article
ISSN: 0002-9610
DOI: 10.1016/j.amjsurg.2008.10.007

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## Abstract Ascochlorin, a non‐toxic prenylphenol compound derived from the fungus __Ascochyta viciae__, has been shown recently to have anti‐cancer effects on various human cancer cells. However, the precise molecular mechanism of this anti‐cancer activity remains to be elucidated. Here, we invest