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Tautomerism of 4-methylhistamine—Effect of the methyl substituent

✍ Scribed by J. C. Emmett; C. R. Ganellin; M. J. Graham; F. H. Holloway

Publisher
SP Birkhäuser Verlag Basel
Year
1979
Tongue
English
Weight
156 KB
Volume
9
Category
Article
ISSN
1420-908X

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## Abstmct: The a@ sub&umts at positions 4 and 6 do not erert observable &unmic cffcts on the ting-chain tautomeric mtios of 2,4-or 2,6-aTaqbubstituted-tetmhydm-1,~~. On the other hand, the ekaivnic @ect of the Z-a~yl subs&em is mat&& in all eight seties s&die4 the equilibria CM be desctibed @ the