Taurine, a possible urinary marker of liver damage: a study of taurine excretion in carbon tetrachloride-treated rats
β Scribed by Catherine J. Waterfield; John A. Turton; M. David C. Scales; John A. Timbrell
- Publisher
- Springer-Verlag
- Year
- 1991
- Tongue
- English
- Weight
- 789 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0340-5761
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## Abstract The influence of chronic hepatic failure on the disposition kinetics of valproate (VPA) excretion via a phase II reaction was examined in rats treated with carbon tetrachloride (1.0 mg/kg, s.c., 3 times a week) for 2 or 3 months. There was no significant difference in the plasma concent
To study the effect of carbon tetrachloride treatment on hepatic lipid peroxidation and glutathionedependent defence system, rats were injected with carbon tetrachloride (0.2 ml/kg body weight, i.p.) twice weekly for a period of 4 weeks. Carbon tetrachloride treatment caused a significant increase i