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Tau phosphorylation and dephosphorylation in human, primate, and rat brain slices

✍ Scribed by Takac, P.; Kubincova, A.

Book ID: 124109959
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 179 KB
Volume: 15
Category: Article
ISSN: 0197-4580
DOI: 10.1016/0197-4580(94)92607-7

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## Abstract Phosphorylation of tau protein has been suggested as a major mechanism regulating its functions. In assembled brain microtubules, tau is phosphorylated, but additional phosphorylation can be induced in vitro. Supply of excess ATP alone was sufficient to reduce migration of tau on SDS ge