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Task-Dependent Development of Cross-Tolerance to Psychomotor Effects of Lorazepam in Man

โœ Scribed by Aranko, Kari


Book ID
114800542
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
624 KB
Volume
56
Category
Article
ISSN
0001-6683

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Acute administration of lorazepam (0.25 and 0.5 mg/kg) and triazolam (0.075-0.25 mg/kg) significantly reduced the locomotor activity of rats placed in a holeboard for 10 min. Acute injections of lorazepam (0.25 and 0.5 mg/kg) and triazolam (0.05-0.25 mg/kg) also significantly reduced exploration, me