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Tartaric acid derivatives as chiral sources for enantioseparation in liquid chromatography

✍ Scribed by W. Lindner; I. Hirschböck


Book ID
103910639
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
555 KB
Volume
2
Category
Article
ISSN
0731-7085

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✦ Synopsis


Based on a systematic review of the usage of tartaric acid as a chiral source to resolve enantiomeric compounds, a concept is presented for synthesizing new chiral stationary phases utilizing tartaric acid derivatives as the chiral selector. The results indicate that the conformational change of one of the three optically active centres of the chiral selector strongly affects its enantioselectivity for certain types of compound.


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