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TARP Modulation of AMPA Receptor Pharmacology: Polyamine Block and Competitive Antagonism

✍ Scribed by MacLean, David; Bowie, Derek

Book ID
122256467
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
51 KB
Volume
98
Category
Article
ISSN
0006-3495

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## Abstract α‐Amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole propionic acid (AMPA) receptors (AMPAR), subtype of the ionotropic glutamate receptors (IGRs), mediate fast synaptic transmission in the central nervous system (CNS), and are involved in many neurological disorders, as well as being a key player in