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Targeting tumor cell motility as a strategy against invasion and metastasis

โœ Scribed by Wells, Alan; Grahovac, Jelena; Wheeler, Sarah; Ma, Bo; Lauffenburger, Douglas


Book ID
120174422
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
628 KB
Volume
34
Category
Article
ISSN
0165-6147

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Over the past 10 years it has become apparent that invasion and metastasis are extremely complex processes; neoplastic cells must escape from the primary tumor, degrade the extracellular matrix, migrate to distant sites, arrest in the capillaries, and migrate through the basement membrane and underl