𝔖 Bobbio Scriptorium
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Targeting tight junction proteins-significance for drug development

✍ Scribed by Masuo Kondoh; Takeshi Yoshida; Hideki Kakutani; Kiyohito Yagi


Book ID
113568830
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
422 KB
Volume
13
Category
Article
ISSN
1359-6446

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## Abstract Transmembrane proteins known as claudins play a critical role in tight junctions by regulating paracellular barrier permeability. The control of claudin assembly into tight junctions requires a complex interplay between several classes of claudins, other transmembrane proteins and scaff