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Targeting the retroviral ribonuclease H by rational drug design

โœ Scribed by Moelling, Karin

Book ID
115529079
Publisher
Lippincott Williams and Wilkins
Year
2012
Tongue
English
Weight
257 KB
Volume
26
Category
Article
ISSN
0269-9370

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๐Ÿ“œ SIMILAR VOLUMES

Targeting the retroviral ribonuclease H
Targeting the retroviral ribonuclease H by rational drug design
โœ Moelling, Karin ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› Lippincott Williams and Wilkins ๐ŸŒ English โš– 257 KB

Ribonucleases H or RNases H are conserved and exist in almost every organism. They generate and remove RNA primers, which are required for DNA replication. RNases H hydrolyze RNA in RNA-DNA hybrids. RNases H and related enzymes contribute to reduction of gene expression in antisense and small-interf