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Targeting the RAF–MEK–ERK pathway in cancer therapy

✍ Scribed by Clara Montagut; Jeff Settleman

Book ID: 116335127
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 363 KB
Volume: 283
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2009.01.022

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## Abstract Erbin is an ErbB2 binding protein, which belongs to the LAP (leucine‐rich repeat (LRR) and PDZ domain) protein family. We previously reported that Tax1, a protein of the human T‐cell leukemia virus type I (HTLV‐I), associated with Erbin by using Erbin PDZ domain as a bait to screen a hu